Name: DNA test Health
Brand: Eligens
Price: undefined EUR
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DNA test

Health

The most effective way to stay healthy is to prevent illnesses or to catch them early for successful treatment.

A DNA test allows you to find out which diseases you are most hereditarily predisposed to. Based on this information, your doctor will develop a personalised diagnostic programme (blood tests or simple functional tests) and take measures to prevent these diseases in advance.

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X-ray symbol representing personalized disease prevention advice from DNA test results

When we are young, we think that our bodies will remain strong and healthy for a long time to come. After all, in the worst case scenario, we are threatened by a cold or flu. But many serious illnesses come our way sooner than we would like. And cardiovascular diseases and cancer can even appear at a young age.

Cardiovascular diseases, chronic lung diseases, cancer and diabetes are responsible for 85% of deaths worldwide.

These diseases manifest themselves poorly in their early stages, when treatment is cheapest and most effective, but when neglected they lead to a significant reduction in quality of life and ultimately to early death.

It is impossible to prevent all diseases at once. But you don't have to, because every person has a chance to encounter only a few of them. And this set of diseases is not random.

Information about our health status and future risks is contained in our genes. This is our genetic health map.

Determining the genetic risk of diseases is an essential part of a healthy lifestyle. For some diseases genetics play a decisive role, for others it only manifests itself through external factors (multifactorial diseases). Not only genetic testing for hereditary diseases, but also assessing the likelihood of multifactorial diseases can significantly help in their prevention and treatment.

Very often a person has an increased predisposition to those diseases that have occurred in their close relatives.

Information about hereditary predisposition is in our genes. Many processes occurring in the body are programmed into the DNA at a molecular level. Mutations in genes inherited from our parents can lead to malfunctions and diseases.

Gene

CHEK2

Lung cancer

Gene

CHEK2

Lung cancer

Is responsible for the synthesis of a protein that regulates the cell division cycle. When DNA in a cell is damaged, the protein blocks the transition to division, which prevents cancerous tumours from developing. Carriers of mutations in this gene have an increased risk of developing cancer, especially lung cancer.

Gene

APOE

Alzheimer's disease

Gene

APOE

Alzheimer's disease

Protein synthesised from the APOE gene is involved in lipid metabolism in the liver and cholesterol in the brain. Combinations of certain mutations in the gene can lead to a 16-fold increase in the risk of developing Alzheimer's disease.

Gene

HLA-DRB1

Multiple sclerosis

Gene

HLA-DRB1

Multiple sclerosis

One of the genes of the major histocompatibility complex that is responsible for the synthesis of a protein that plays an important role in the immune system. Disorders of the gene can lead to autoimmune diseases, including multiple sclerosis.

Gene

AGBL1

Schizophrenia

Gene

AGBL1

Schizophrenia

This gene codes for glutamate decarboxylase, which is involved in post-translational modifications of various proteins. Mutations in this gene lead to an increased risk of developing schizophrenia, but the molecular mechanism of how the disorders affect the development of this disease is not yet known.

Gene

BRCA1

Ovarian cancer

Gene

BRCA1

Ovarian cancer

This gene codes for a protein which plays an important role in ensuring genome stability, inhibiting oncogenesis and protecting the body against the development of tumours. Mutations in the gene, which disrupt its normal functioning, are the cause of almost 40% of family cases of breast cancer and more than 80% of ovarian cancer.

A healthy diet, regular exercise and avoidance of bad habits are considered the universal formula for active longevity. But even the healthiest lifestyle does not eliminate all risks, and some diseases cannot be prevented or require medical advice. Most diseases are caused by a combination of genetic predispositions and unfavourable environmental factors. Today, medicine cannot change our DNA, but by being aware of genetic risks, it is possible to reduce the adverse effects of certain external factors.

The human body is made up of billions of tiny cells, each one encoded in DNA molecules with information about the body. The genes that determine our personality - our appearance, the way our body functions and the risks of disease - are passed on from generation to generation. For example, Gilbert's disease is associated with a mutation in the gene and abnormal metabolism of the pigment bilirubin. A genetic test can help identify a predisposition to this syndrome and your doctor can develop preventative and diagnostic measures.

Thousands of customers are satisfied with our services

“The DNA analysis revealed my Peruvian roots and also information about my genetic predispositions to certain diseases. Now I can make informed decisions to live an even healthier life. Thank you, Eligens”

Bruno Diaz

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Dangerous genes

Although the basic property of genetic information is that it is precisely self-copied, which allows for the hereditary transmission of many traits from parent to child, genes can be altered. Such changes - self-copying errors - are called genetic polymorphisms. And it is polymorphisms that create the variability necessary for evolution and the diversity of life forms. But these same polymorphisms can partially or completely shut down individual genes, leading to dysfunction of entire organ systems.

Being inherently errors in the transmission of genetic material, polymorphisms are random and non-directional, that is, they can be both beneficial and harmful. Useful polymorphisms are fixed in the course of evolution and form the basis for the progressive development of life on Earth, and harmful ones - mutations that reduce viability - are the other side of the coin. They are the basis of hereditary diseases. And it is these that the genetic test for disease detection by DNA identifies.

Diseases of the cardiovascular system

Cardiovascular diseases are the most frequent cause of death in the world, with one of every two deaths caused by vascular problems, damage to the heart muscle or impaired nerve impulse conduction in the heart. Genetic factors inherited from parents play a significant role in the development of all these conditions.

For example, the presence of atherosclerosis in one parent increases the risk of developing the disease in children by 3-fold.

However, apart from genetic factors, which modern medicine is unable to change, the development of cardiovascular disease and influenced by environmental factors, by influencing which it becomes possible to manage the overall risk of developing a particular disease.

Diseases under investigation:

Abdominal aortic aneurysm
Venous thromboembolism
Sudden coronary death
Hypertension
Myocardial hypertrophy
Dilation cardiomyopathy
Myocardial infarction
Coronary heart disease
Atrial fibrillation and/or atrial flutter
Brugada syndrome

Diseases of the respiratory system

The respiratory system plays a vital role in delivering oxygen to the body. It also removes carbon dioxide from the body, participates in thermoregulation and maintains optimal blood pH. Infections, as well as genetic factors, can cause both non-dangerous and fatal respiratory diseases, such as asthma and lung cancer.

More than 25% of cancer deaths in Russia are caused by neoplasms of the respiratory system, primarily lung cancer. Unfortunately, the initial stages of lung cancer are practically invisible, and in later stages treatment is ineffective.

Identifying genetic factors in the development of respiratory diseases, including lung cancer, will allow optimal screening intervals to be planned for early detection, and preventive measures will reduce the cumulative risk.

Diseases under investigation:

Allergic rhinitis
Allergic sensitization
Asthma
Collagen disease of the lung
Airway obstruction
Upper respiratory cancer
Lung cancer
Chronic Obstructive Pulmonary Disease

Diseases of the nervous system

The human nervous system is a complex structure that controls all the activities of our body. It includes the central nervous system (spinal cord and brain), as well as the peripheral nervous system - the nerves and the sensory organs. Various kinds of disease can be life-threatening - neurodegenerative (Alzheimer's and Parkinson's diseases), cancer (gliomas, glioblastomas, neuroblastomas), autoimmune (multiple sclerosis), brain circulation disorders (strokes), and mental illness (such as schizophrenia).

Scientists do not fully understand all the mechanisms of nervous system diseases, but it has been established that genetic factors play a key role for most of them. Doctors cannot change our genes, but timely prevention will reduce the risk of serious consequences, and early screening will reveal the first disorders when therapy is most effective.

DNA test examines genetic markers of stroke susceptibility that have been identified by Eligens researchers.

Diseases under investigation:

Alcoholism
Bipolar disorder
Amyotrophic lateral sclerosis
Alzheimer's disease
Parkinson's disease
Glioblastoma
Glioma
Depression
Ischemic stroke
Migraine
Narcolepsy
Mood disorders
Neuroblastoma
Multiple sclerosis
Attention deficit syndrome
Schizophrenia
Generalised epilepsy

Diseases of the digestive system

The health of your digestive system is strongly influenced by your lifestyle - the food you eat, exercise, and stress. However, many diseases, such as stomach cancer, colorectal cancer and Crohn's disease, have hereditary causes.

Crohn's disease, for example, often runs in families. One in five patients has a parent or other close relative who also has it. Information about genetic predisposition helps doctors predict the course of the disease, including the risks of complications, the need for surgery and the patient's response to drug therapy.

Diseases under investigation:

Adenocarcinoma of the oesophagus
Crohn's disease
Carcinoid of the ileum
Colorectal cancer
Pancreatitis
Primary biliary cirrhosis
Primary sclerosing cholangitis
Periodontitis
Pancreatic cancer
Celiac disease
Ulcerative colitis

Diseases of the musculoskeletal system

Every connective tissue disease has different symptoms. Some diseases may cause problems with bone growth - the bones may be brittle, too long or short. Some diseases lead to weak joints, frequent tendon ruptures and skin damage. Often the body's immune system starts to attack the proteins that make up the connective tissue - in this case autoimmune diseases develop.

Genetic factors can predispose a person to the development of autoimmune diseases such as rheumatoid arthritis. The main manifestation of such diseases is an overactive immune system, which leads to excessive production of antibodies. Each disease can develop slowly or very rapidly, and the manifestations can be both classic and baffling even to experienced doctors.

It is not possible to prevent all diseases of the bones and connective tissue at the same time, but genetic testing will identify risks that should be taken into account. Early diagnosis and adherence to the preventive recommendations of the attending physician will minimise the risks of negative consequences.

Diseases under investigation:

Osteoarthritis of the knee
Osteoarthritis
Dupuytren's contracture
Rheumatoid arthritis
Bechterew's disease
Juvenile idiopathic arthritis
Psoriatic arthritis
Osteonecrosis of the jaw
Kawasaki syndrome
Behcet's disease

187 Other multifactorial and hereditary diseases

Male pattern baldness
Acne (pimples)
Psoriasis
Vitiligo
Alopecia nestle
Cardiovascular diseases
Hypertension
Myocardial hypertrophy
Myocardial infarction
Coronary heart disease
Venous thromboembolism

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Atrial fibrillation and/or atrial flutter
Abdominal aortic aneurysm
Dilation cardiomyopathy
Atrial fibrillation
Brugada syndrome
Sudden coronary death
Psychiatric disorders
Tobacco smoking
Neuroticism
Depression
Bipolar disorder
Suicidal thoughts
Tourette's syndrome
Schizophrenia
Alcoholism
Anorexia nervosa
Marijuana addiction
Depression and alcoholism
Creutzfeldt-Jakob disease
Digestive diseases
Periodontitis
Demineralisation of molar incisors
Combined oesophageal disease (Barrett's oesophagus and adenocarcinoma of the oesophagus)
Barrett's oesophagus
Celiac disease
Hypertrophic pyloric stenosis in children
Chronic inflammatory bowel disease
Crohn's disease
Helicobacter Pylori serologic status
Pancreatitis
Ulcerative colitis
Primary biliary cirrhosis
Primary sclerosing cholangitis
Allergic diseases
Allergic sensitization
Atopic dermatitis
Atopy
Allergic rhinitis
Diseases of the nervous system
Migraine
Migraine with aura
Migraine without aura
Ischemic stroke
Mood disorders
Intracranial aneurysm
Essential tremor
Generalised epilepsy
Attention deficit syndrome
Restless legs syndrome
Alzheimer's disease
Parkinson's disease
Narcolepsy
Multiple sclerosis
Amyotrophic lateral sclerosis
Myasthenia gravis
Amyotrophic lateral sclerosis (sporadic form)
Progressive supranuclear palsy
Respiratory diseases
Asthma
Chronic obstructive pulmonary disease
Bronchoobstructive syndrome
Idiopathic fibrosing alveolitis
Metabolic diseases
Obesity
Diabetes mellitus type 2
Hypothyroidism
Hypertriglyceridemia
Gout
Osteoporosis
Type 1 diabetes mellitus
Illnesses of urogenital system
Urinary stone disease
Chronic kidney disease
Hypospadias
IgA - nephropathy
Diseases of the musculoskeletal system
Osteoarthritis of the knee
Osteoarthritis
Dupuytren's contracture
Rheumatoid arthritis
Bechterew's disease
Juvenile idiopathic arthritis
Psoriatic arthritis
Osteonecrosis of the jaw
Kawasaki syndrome
Behcet's disease
Eye disease
Age-related macular degeneration
Corneal endothelial dystrophy
Glaucoma
Myopia
Retinal detachment
Malignant neoplasms
Paget's disease
Bladder cancer
Upper respiratory cancer
Renal cancer
Pancreatic cancer
Thyroid cancer
Basalioma
Prostate cancer
Colorectal cancer
Lung cancer (small cell)
Lung adenocarcinoma
Non-small cell lung cancer
Nephroblastoma
Testicular cancer
Melanoma
Glioblastoma
Adenocarcinoma of the oesophagus
Testicular germ cell carcinoma
Glioma
Neuroblastoma
Carcinoid of the ileum
Osteogenic sarcoma
Ewing sarcoma
Systemic connective tissue diseases
Neonatal lupus
Systemic lupus erythematosus
Sarcoidosis
Systemic scleroderma
Blood Diseases
Childhood acute lymphoblastic leukemia
Lymphoma
Follicular lymphoma
Hodgkin lymphoma
Chronic lympho leukaemia
Myeloproliferative tumours
Multiple myeloma
Infection prone
Malaria
Prion diseases
Meningococcal infection
malformations
Tetrada fallo
Sagittal craniosynostosis
Hare's lip
Orofacial clefts
Ear diseases
Otosclerosis

Good health and a young age do not guarantee that there are no serious hidden health problems. A genetic test helps to identify risks and create an individualised programme of prevention and screening.

Depending on the genetic predispositions found, a family doctor can design an individual screening programme (check-up) and prevention that will reduce or completely eliminate the risks of serious diseases.

Prevention

Lifestyle changes can help reduce the risk of disease. Get a genetic test for cancer, diabetes, allergies and other diseases that could affect you now or in the future. You will be given advice which, if followed, will reduce your chances of getting ill and, in some cases, prevent the development of diseases.

For example, since the introduction of blood pressure lowering drugs, the rate of critical emergencies in patients with hypertension has fallen from 7% to approximately 1%, and the one-year survival rate associated with critically high blood pressure (hypertensive crisis) has increased from 20% to more than 90% with the right medication.

Check-up

Most genetic risks are realised through environmental and lifestyle influences. There are some diseases that cannot be prevented by lifestyle changes or medical prevention measures, but their early detection increases the chances of recovery, often approaching 100%. Knowing your genetic risks, a personalised plan of examinations (functional and laboratory tests) and specialist consultations will be drawn up for you, during which you will be able to detect the first signs of diseases in good time, when therapy is most effective.

For example, a complete cure of breast cancer in stage 1, when the size of the tumour is less than a few millimetres, is possible in 95% of those affected, while in stage 3 (with a tumour of 1-2 centimetres), it is less than 50%. The genetic test for cancer identifies individual risks, and the doctor draws up a screening plan based on these risks.

Welcome to the future

The DNA test allows you to find out which diseases are at higher risk due to a combination of hereditary predisposition, lifestyle and external influences. This will enable you to take steps in advance to diagnose and prevent the progression of these diseases.

Worldwide delivery of the DNA test

We deliver the box to you, you study the enclosed instructions (or carefully read our website), submit your saliva and send the test back to us. All you have to do is wait for the results.

How to take the test

Receiving and analyzing the data

Specialists at the best laboratories in the world decode the sequence of your DNA fragments and interpret them. Usually the file obtained from this analysis weighs about 30 MB. The study takes 4-6 weeks but may take up to 60 days.

Access to personal data

The final results and recommendations are stored in your private office. There you will also collect the data you receive when you do a new site survey.

My Account

Personal information is stored in your personal cabinet and is only available after you have logged in, so no one will see it without your knowledge. As science advances every day, new methods are becoming available that allow us to decipher additional sections of DNA.

So stay tuned for more updates! In the meantime, see what we offer today.

Dashboard displaying genetic risk factors for diseases based on DNA test results

DNA risks of disease development

Identify the presence of genetic markers associated with the development of more than 187 diseases, including diseases of the cardiovascular and nervous system

Advice on preventing diseases

You will receive recommendations which, if followed, will reduce your chances of becoming ill and, in some cases, prevent the development of a disease.